Від складної кардіоміопатії з поєднаною обструкцією виносного тракту лівого шлуночна та кальцинованого жорсткого лівого передсердя – до трансплантації ‘серце-легені’
Ключові слова:
hypertrophic cardiomyopathy, subaortic fibromuscular membrane, stiff left atrial syndrome, left atrial calcification, atrial fibrillation, transcatheter modification, pulmonary hypertension, heart-lung transplantationКороткий опис
Reviewers:
Todurov Borys Mychailovych, Corresponding Member of the Academy of Medical Sciences of Ukraine, Doctor of Medical Sciences, Professor, Honored Doctor of Ukraine; Heart Institute of the Ministry of Health of Ukraine, Kyiv, Ukraine
Nesukay Olena Gennadiivna, MD, Doctor of Medical Sciences, Professor; National Scientific Center «M.D. Strazhesko Institute of Cardiology, Clinical and Regenerative Medicine» of NAMS of Ukraine, Kyiv, Ukraine
Vasilyeva L.I., Kalashnykova O.S.
Complex cardiomyopathy with combined left ventricle outflow tract obstruction and calcified stiff left atrium: the pathway to heart-lung transplantation: Monograph /
L. Vasilyeva, O. Kalashnykova. – Karlsruhe: ScientificWorld-NetAkhatAV,
2026. – 133 p.
Від складної кардіоміопатії з поєднаною обструкцією виносного тракту лівого шлуночна та кальцинованого жорсткого лівого передсердя – до трансплантації ‘серце-легені’: монографія / Л. Васильєва, О. Калашникова - Карлсруе, 2026. – 133 с.
The monograph presents the clinical course of a female patient with an exceptionally complex form of cardiomyopathy—hypertrophic cardiomyopathy (HCM) accompanied by a subaortic muscular membrane and a mixed (fixed and dynamic) obstruction of the left ventricular outflow tract (LVOT).
Her medical history includes multiple intricate interventions for atrial fibrillation and flutter, which ultimately resulted in the development of stiff left atrial (Stiff LA) syndrome, characterized by irreversible calcification of the left atrial wall. The clinical condition is further complicated by severe, likely mixed-type pulmonary hypertension, associated with aneurysmal dilatation of the pulmonary artery.
Despite a preserved left ventricular ejection fraction and maintained sinus rhythm, subtotal calcification of the left atrium with morphologically driven restriction of venous outflow excludes the option of isolated lung transplantation. The extent of structural damage involving both the heart and pulmonary vasculature supports combined heart–lung transplantation as the only viable therapeutic approach, in accordance with current international guidelines (ISHLT, ESC/ERS, WSPH). However, such procedures currently exceed the available expertise and capacity within the Ukrainian healthcare system.
This monograph is multidisciplinary in scope and offers practical value for cardiologists, cardiac surgeons, pulmonologists, and transplant specialists.
ISBN 978-3-98924-123-7
DOI: 10.30890/978-3-98924-123-7.2026
Розділи
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ЧАСТИНА 1. СТРУКТУРОВАНИЙ КЛІНІЧНИЙ РОЗБІР ІЗ ВИСНОВКАМИ ЩОДО ТАКТИКИ ВЕДЕННЯ
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ЧАСТИНА 2. АНАЛІТИЧНИЙ ОГЛЯД ДОКАЗІВ, СТРАТЕГІЙ ТА НАВЧАЛЬНИХ АСПЕКТІВ
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ЧАСТИНА 3. ІЛЮСТРАЦІЇ ДО КЛІНІЧНОГО ВИПАДКУ
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ЧАСТИНА 4. ОПИТУВАЛЬНІ ФОРМИ ДЛЯ УЧАСНИКІВ ОСВІТНЬОГО ПРОЦЕСУ
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